English, Article edition: Antidepressant Selection and Use and Healthcare Expenditures: An Empirical Approach William H. Crown; Timothy R. Hylan; Laurie Meneades

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Physical Description
  • article
Language
  • English

Edition details

Title
  • Antidepressant Selection and Use and Healthcare Expenditures: An Empirical Approach
Author
  • William H. Crown
  • Timothy R. Hylan
  • Laurie Meneades
Physical Description
  • article
Notes
  • The purpose of this study was to evaluate whether 1-year total healthcare expenditures differed between patients who initiated therapy on a tricyclic antidepressant (TCA) or a selective serotonin reuptake inhibitor (SSRI) after controlling for initial antidepressant selection and antidepressant use pattern. A retrospective claims database covering a privately insured population in the US was used. Patients who initiated therapy in the outpatient setting (primary care or psychiatrist) were considered. Two-stage sample selection models were estimated that included controls for initial antidepressant selection and use pattern. The analyses indicated that: 1. self-selection due to initial antidepressant selection was a statistically significant determinant of expenditures for patients who initiated therapy on a TCA but not an SSRI 2. after controlling for initial antidepressant selection, antidepressant use pattern was a statistically significant and positive determinant of expenditures for both TCA and SSRI patients; and 3. after controlling for initial antidepressant selection and use pattern, 1-year total direct healthcare expenditures were significantly lower for patients who initiated therapy on an SSRI than for patients who initiated therapy on a TCA.
  • Pharmacoeconomics, Healthcare-expenditure, Depression, Serotonin-uptake-inhibitors, Tricyclic-antidepressants, Cost-analysis, Drug-utilisation
  • RePEc:wkh:phecon:v:13:y:1998:i:4:p:435-448
Language
  • English
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