English, Article edition: Cost Effectiveness of Multi-Therapy Treatment Strategies in the Prevention of Vertebral Fractures in Postmenopausal Women with Osteoporosis Andrew J. Rosner; Daniel T. Grima; George W. Torrance; ...

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Physical Description
  • article
Language
  • English

Edition details

Title
  • Cost Effectiveness of Multi-Therapy Treatment Strategies in the Prevention of Vertebral Fractures in Postmenopausal Women with Osteoporosis
Author
  • Andrew J. Rosner
  • Daniel T. Grima
  • George W. Torrance
  • Cathy Bradley
  • Jonathan D. Adachi
  • Rolf J. Sebaldt
  • Donald J. Willison
Physical Description
  • article
Notes
  • Objective: The aim of this study was to evaluate the cost effectiveness of multi-therapy treatment strategies in the prevention of vertebral fractures in postmenopausal women with osteoporosis. Design: A retrospective, incremental cost-effectiveness analysis was conducted from a societal perspective. It compared 9 treatment strategies over 3 years and incorporated the willingness of patients to initiate and continue each therapy. Main outcome measures and results: Four nondominated strategies formed the efficient frontier in the following order: 1. calcium -> no therapy; 2. ovarian hormone therapy (OHT) -> calcium -> no therapy [166 Canadian dollars ($Can)]; 3. OHT -> etidronate -> calcium -> no therapy ($Can2331); and 4. OHT -> alendronate -> calcium -> no therapy ($Can40 965). The figures in parentheses are the incremental costs per vertebral fracture averted to move to that strategy from the previous strategy for patients who had undergone a hysterectomy. Conclusions: We identified 4 efficient multi-therapy strategies for the treatment of vertebral osteoporosis in postmenopausal women, 2 of which were consistent with the practice guidelines of the Osteoporosis Society of Canada. Decision-makers may select from among these efficient strategies on the basis of incremental cost effectiveness.
  • Postmenopausal-osteoporosis, Pharmacoeconomics, Cost-effectiveness, Etidronic-acid, Calcium, Alendronic-acid, Estrogens, Estradiol, Cost-utility, Quality-adjusted-life-years, Vertebral-fracture, Osteoporosis-therapies, Menopause
  • RePEc:wkh:phecon:v:14:y:1998:i:5:p:559-573
Language
  • English
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