English, Article edition: Symptom and Health-Related Quality-of-Life Measures for Use in Selected Gastrointestinal Disease Studies: A Review and Synthesis of the Literature Anne M. Rentz; Carmelina Battista; Elyse Trudeau; ...

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Bookmark: http://trove.nla.gov.au/version/94650
Physical Description
  • article
Language
  • English

Edition details

Title
  • Symptom and Health-Related Quality-of-Life Measures for Use in Selected Gastrointestinal Disease Studies: A Review and Synthesis of the Literature
Author
  • Anne M. Rentz
  • Carmelina Battista
  • Elyse Trudeau
  • Robert Jones
  • Patricia Robinson
  • Sheldon Sloan
  • Sonika Mathur
  • Lori Frank
  • Dennis A. Revicki
Physical Description
  • article
Notes
  • Patient-rated symptom and health-related quality-of-life (HR-QOL) outcomes are important end-points for clinical trials of medical treatments for gastrointestinal (GI) disorders. Based on this review, patient outcomes research is focused on gastroesophageal reflux disease and dyspepsia, with a growing interest in irritable bowel syndrome but little research in gastroparesis. State-of-the-art for patient-rated symptom scales is rudimentary with an abundance of scales and little attention to systematic instrument development or comprehensive psychometric evaluation. Generally, disease-specific HR-QOL measures have been more systematically developed and evaluated psychometrically, but few have been incorporated into clinical trials. More comprehensive outcome assessments are needed to determine the effectiveness of new medical treatments for functional GI disorders. Future clinical trials of GI disorders should combine clinician assessments of outcomes and symptoms with patient-rated symptom and HR-QOL end-points.
  • Dyspepsia, Gastro oesophageal reflux, Gastrointestinal disorders, Gastroparesis, Heartburn, Irritable bowel syndrome, Pharmacoeconomics, Quality of life, Quality of life rating scales
  • RePEc:wkh:phecon:v:19:y:2001:i:4:p:349-363
Language
  • English
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