English, Article edition: Prevalence and Management of Anemia Among Patients with Chronic Kidney Disease in a Health Maintenance Organization Annamaria T. Kausz; Earl P. Steinberg; Allen R. Nissenson; ...

User activity

Share to:
 
Bookmark: http://trove.nla.gov.au/version/92226
Physical Description
  • article
Language
  • English

Edition details

Title
  • Prevalence and Management of Anemia Among Patients with Chronic Kidney Disease in a Health Maintenance Organization
Author
  • Annamaria T. Kausz
  • Earl P. Steinberg
  • Allen R. Nissenson
  • Brian J.G. Pereira
Physical Description
  • article
Notes
  • Background: Anemia often develops among patients with chronic kidney disease (CKD) and is an important cause of cardiovascular disease among patients with end-stage renal disease (ESRD). Objective: To evaluate the epidemiology and treatment of anemia among patients with CKD by undertaking an analysis of data from one Health Maintenance Organization. Methods: The CKD cohort was comprised of 1658 patients followed between 1 January 1994 and 1 December 1997 who had serum creatinine (SCr) levels above gender-specific norms. The prevalence of anemia and epoetin-alpha (recombinant human erythropoietin) use was determined, and the association with anemia and kidney function was assessed with multinomial logistic regression analysis. Results: 36% of patients with CKD had anemia, with at least two hematocrit (HCT) values (separated by >=​30 days) lower than the gender-specific norm (<42% for males, <36% for females). Eleven per cent of patients had a lowest HCT value less than the gender-specific norm but >=​33%, 6% had a lowest HCT value 30 to 32.9%, and 19% had a lowest HCT value <30%. The prevalence of anemia was positively correlated with the severity of kidney dysfunction. In the multivariate analysis, the independent relative risk of an HCT value <30% versus no anemia was 84.5, 9.8 and 2.0 for patients with SCr level >=​4.0, 3.0 to 3.9 and 2.0 to 2.9 mg/​dl, respectively, compared with patients with SCr level <2.0 mg/​dl. Epoetin-alpha was prescribed for only 7.4% of patients and, more significantly, for only 23% of patients with an HCT value <30%. Even among patients with an HCT value <30% who had received care from a nephrologist, only 66% received epoetin-alpha. Conclusions: This study demonstrates that the prevalence of anemia among patients with CKD is high and the management of anemia is suboptimal. Suboptimal treatment of anemia during CKD may lead to increased cardiovascular morbidity and cost of care among patients with CKD and ESRD.
  • Anaemia, Antianaemics, Drug utilisation, Epoetin alfa, Pharmacoeconomics
  • RePEc:wkh:dmhout:v:10:y:2002:i:8:p:505-513
Language
  • English
Contributed by
OAIster

Get this edition

  • Set up My libraries

    How do I set up "My libraries"?

    In order to set up a list of libraries that you have access to, you must first login or sign up. Then set up a personal list of libraries from your profile page by clicking on your user name at the top right of any screen.

  • All (1)
  • Unknown (1)
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.

User activity


e.g. test cricket, Perth (WA), "Parkes, Henry"

Separate different tags with a comma. To include a comma in your tag, surround the tag with double quotes.

Be the first to add a tag for this edition

Be the first to add this to a list

Comments and reviews

What are comments? Add a comment

No user comments or reviews for this version

Add a comment