English, Article edition: Association of Pre-Existing Symptoms with Treatment Decisions among Newly Diagnosed Prostate Cancer Patients Steven B. Zeliadt; Scott D. Ramsey; Arnold L. Potosky; ...

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Bookmark: http://trove.nla.gov.au/version/45995
Physical Description
  • article
Language
  • English

Edition details

Title
  • Association of Pre-Existing Symptoms with Treatment Decisions among Newly Diagnosed Prostate Cancer Patients
Author
  • Steven B. Zeliadt
  • Scott D. Ramsey
  • Arnold L. Potosky
  • Neeraj K. Arora
  • David K. Blough
  • Ingrid Oakley-Girvan
  • Ann S. Hamilton
  • Stephen K. Van Den Eeden
  • David F. Penson
Physical Description
  • article
Notes
  • Background: The choice between surgical and non-surgical treatment options is a fundamental decision for men with local-stage prostate cancer because of differences in risks of genitourinary adverse effects among available treatments. Objectives: We assessed whether pre-existing genitourinary symptoms at the time of diagnosis influenced men's preferences for surgery over other management options. Methods: We recruited 593 patients with newly diagnosed local-stage prostate cancer prior to initiating treatment from an integrated healthcare system, an academic urology center, and community urology clinics. We used logistic regression to compare whether men had a preference for non-surgical options or only preferred surgery. Results: Nearly 60% of participants indicated that they were considering non-surgical options. Age and clinical characteristics but not pre-existing genitourinary symptoms influenced the decision between surgical or non-surgical options. A total of 62% of men reported adverse effects as a main factor in their treatment decision. Men with more aggressive tumor types were less likely to consider adverse effects; however, men who reported poor ability to have an erection were more likely to consider adverse effects in their treatment decision (p_<_0.001). Conclusion: Sexual dysfunction at time of diagnosis, but not other genitourinary symptoms, is associated with men considering treatment-related adverse effects when considering surgery versus other options. Men who are not experiencing sexual dysfunction at diagnosis may discount the risks of adverse effects in the decision-making process. DOI: 10.2165/​1312067-200801030-00006
  • Androgen-receptor-antagonists, Patient-preference, Prostate-cancer, Prostatic-surgery, Radiotherapy
  • RePEc:wkh:thepat:v:1:y:2008:i:3:p:189-200
Language
  • English
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