2007, Eng, eng , Thesis edition: Probiotic characteristics of Lactobacillus acidophilus and Lactobacillus paracasei and their effects on immune response and gene expression in mice Paturi, Gunaranjan

User activity

Send to:
 
Bookmark: http://trove.nla.gov.au/version/47258101
Physical Description
  • THESIS
Published
  • 2007
Language
  • Eng
  • eng

Edition details

Title
  • Probiotic characteristics of Lactobacillus acidophilus and Lactobacillus paracasei and their effects on immune response and gene expression in mice
Author
  • Paturi, Gunaranjan
Published
  • 2007
Physical Description
  • THESIS
Subjects
Summary
  • Probiotic bacteria such as Lactobacillus and Bifidobacterium species are normal inhabitants of healthy gastrointestinal (GI) tract, which may promote beneficial effects on host through limiting the growth of undesirable micro-organisms and modulating the immune system. In the present study, Lactobacillus and Bifidobacterium strains were screened for their in vitro acid and bile tolerance, autoaggregation, coaggregation and hydrophobic abilities to identify potential probiotic bacteria. Lactobacillus acidophilus LAFTI L10 and Lactobacillus paracasei LAFTI L26 were selected based on their overall tolerance to in vitro acidic conditions to further investigate their influence on various immune functions and gene expression in mice. Immunofluorescent analysis of small intestine in mice fed with L. acidophilus or L. paracasei demonstrated an increase of immunoglobulin (Ig)-A, interleukin (IL)-10 and interferon (IFN)- producing cells compared to control mice. In summary, L. acidophilus and L. paracasei showed tolerance to various gastric conditions and bile salts. Lactobacillus acidophilus and L. paracasei enhanced gut and systemic immune functions, particularly non-specific and specific immune responses in normal and CT mice. Moreover, L. acidophilus regulated the genes involved in various biological functions in small bowel of normal and CT mice, which provided a basis in understanding the pathways through which these bacteria are beneficial to the host.
  • Doctor of Philosophy (PhD)
Language
  • Eng
  • eng
Identifier
  • oai:arrow.uws.edu.au:uws:2504

Get this edition

With access conditions

  • Set up My libraries

    How do I set up "My libraries"?

    In order to set up a list of libraries that you have access to, you must first login or sign up. Then set up a personal list of libraries from your profile page by clicking on your user name at the top right of any screen.

  • All (1)
  • NSW (1)
None of your libraries hold this item.
None of your libraries hold this item.

This single location in New South Wales:

Library Access Call number(s) Formats held Language
University of Western Sydney. Ward Library. Open to the public Thesis Eng; eng
Show 0 more libraries...
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.

User activity


e.g. test cricket, Perth (WA), "Parkes, Henry"

Separate different tags with a comma. To include a comma in your tag, surround the tag with double quotes.

Be the first to add a tag for this edition

Be the first to add this to a list

Comments and reviews

What are comments? Add a comment

No user comments or reviews for this version

Add a comment