2006, English, Article edition: Delays in Biological Regulatory Networks Ahmad, Jamil; Richard, Adrien; Bernot, Gilles; ...

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Bookmark: http://trove.nla.gov.au/version/209733
Physical Description
  • text
Published
  • HAL - CCSD
  • 2006
Language
  • English

Edition details

Title
  • Delays in Biological Regulatory Networks
Author
  • Ahmad, Jamil
  • Richard, Adrien
  • Bernot, Gilles
  • Comet, Jean-Paul
  • Roux, Olivier
Published
  • HAL - CCSD
  • 2006
Physical Description
  • text
Subjects
Notes
  • In this article, we propose a refinement of the modeling of genetic regulatory networks based on the approach of René Thomas. The notion of delays of activation/​inhibition are added in order to specify which variable is faster affected by a change of its regulators. The formalism of linear hybrid automata is well suited to allow such refinement. We then use HyTech for two purposes: (1) to find automatically all paths from a specified initial state to another one and (2) to synthesize co nstraints on the delay parameters in order to follow any specific path.
  • HAL:hal-00341972, version 1
  • HAL:http:/​/​hal.archives-ouvertes.fr/​hal-00341972/​en/​
  • DOI:10.1007/​11758525_118
Language
  • English
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