1962, English, Article edition: CLINICAL STUDIES OF INDUCTION AGENTS: III: THE RELATIONSHIP BETWEEN DURATION OF ANAESTHESIA AND DOSAGE WITH G.29.505 DUNDEE, JOHN W.

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Bookmark: http://trove.nla.gov.au/version/209626
Physical Description
  • text/​html
Published
  • Oxford University Press
  • 1962-11-01 00:00:00.0
Language
  • English

Edition details

Title
  • CLINICAL STUDIES OF INDUCTION AGENTS: III: THE RELATIONSHIP BETWEEN DURATION OF ANAESTHESIA AND DOSAGE WITH G.29.505
Author
  • DUNDEE, JOHN W.
Published
  • Oxford University Press
  • 1962-11-01 00:00:00.0
Physical Description
  • text/​html
Subjects
Notes
  • In seventy−seven fit patients, premedicated only with atropine, a linear relationship was found between the dosage of G.29.505 (range 100–800 mg; 1.8–18.1 mg&​sol;kg) and sleeping time. This differs from the expected response to similar doses of thiopentone. The difference in recovery from the two drugs may be attributable to variations in their redistribution (and possibly detoxication) in the body. It is postulated that the lack of depressant effects of G.29.505 on the cardiovascular system, and release of adrenaline after injection, may contribute to the rapid recovery, even after large doses, from the effects of this drug.
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  • Copyright (C) 1962, Oxford University Press
Language
  • English
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