2008, English, Article edition: Major weight loss prevents long-term left atrial enlargement in patients with morbid and extreme obesity Garza, Carolina A.; Pellikka, Patricia A.; Somers, Virend K.; ...

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Physical Description
  • text/​html
Published
  • Oxford University Press
  • 2008-09-01 00:00:00.0
Language
  • English

Edition details

Title
  • Major weight loss prevents long-term left atrial enlargement in patients with morbid and extreme obesity
Author
  • Garza, Carolina A.
  • Pellikka, Patricia A.
  • Somers, Virend K.
  • Sarr, Michael G.
  • Seward, James B.
  • Collazo-Clavell, Maria L.
  • Oehler, Elise
  • Lopez-Jimenez, Francisco
Published
  • Oxford University Press
  • 2008-09-01 00:00:00.0
Physical Description
  • text/​html
Subjects
Notes
  • Aims To assess long-term changes in left atrial (LA) volume in patients with morbid obesity [body mass index (BMI) ≥35 kg/​m2 with co-morbidities] and extreme obesity (BMI ≥40 kg/​m2), after surgically-induced weight loss (WL) after gastric bypass surgery. Methods and results We reviewed 57 patients who underwent gastric bypass surgery and had echocardiograms both before and after the operation. A control group was frequency-matched for BMI, sex, age, and for duration of follow-up. After a mean follow-up of 3.6 years, LA volume did not change significantly in patients who underwent bariatric surgery, but increased in the control group by 15 ± 28 ml ( P < 0.0001), and 0.1 ± 0.2 ml ( P < 0.0001) for height-indexed LA volume, with a difference between cases and controls that remained significant after adjusting for potential confounders ( P =​ 0.01). In the study population as a whole, there was a positive correlation between change in body weight and change in LA volume ( r =​ 0.22, P =​ 0.006) independent of clinical conditions associated with LA enlargement. Conclusion Change in body weight is associated with change in LA size independent of obesity-associated co-morbidities. Successful WL induced by bariatric surgery prevents the progressive increase in LA volume.
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  • Copyright (C) 2008, European Society of Cardiology
Language
  • English
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