2009, English, Article edition: A Boolean Model of Molecular Signaling Pathways Niel, Olivier

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Bookmark: http://trove.nla.gov.au/version/208844
Physical Description
  • text
Published
  • HAL - CCSD
  • 2009
Language
  • English

Edition details

Title
  • A Boolean Model of Molecular Signaling Pathways
Author
  • Niel, Olivier
Published
  • HAL - CCSD
  • 2009
Physical Description
  • text
Subjects
Notes
  • The usual representation of signaling pathways in molecular biology consists of diagrams. These diagrams are often unclear and confusing, thus making global understanding, prediction and computerization of the signaling pathways impossible. Here we propose a novel representation of signaling pathways, based on a mathematical model. This model associates a simple equation with any signaling pathway. We used this model to study several pathways, such as Akt, leading to strong predictions and powerful in silico experiments.
  • HAL:hal-00405173, version 1
  • HAL:http:/​/​hal.archives-ouvertes.fr/​hal-00405173/​en/​
Language
  • English
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