1998, English, Article edition: A comparative prospective study of a chronic low dose versus a conventional ovulation stimulation regimen using recombinant human follicle stimulating hormone in anovulatory infertile women Hedon, B.; Hugues, J.N.; Emperaire, J.C.; ...

User activity

Share to:
 
Bookmark: http://trove.nla.gov.au/version/205498
Physical Description
  • text/​html
Published
  • Oxford University Press
  • 1998-10-01 00:00:00.0
Language
  • English

Edition details

Title
  • A comparative prospective study of a chronic low dose versus a conventional ovulation stimulation regimen using recombinant human follicle stimulating hormone in anovulatory infertile women
Author
  • Hedon, B.
  • Hugues, J.N.
  • Emperaire, J.C.
  • Chabaud, J.J.
  • Barbereau, D.
  • Boujenah, A.
  • Howles, C.M.
  • Truong, F.
Published
  • Oxford University Press
  • 1998-10-01 00:00:00.0
Physical Description
  • text/​html
Subjects
Notes
  • The efficacy and safety of a chronic low dose (group A) and a conventional (group B) stimulation regimen of recombinant human follicle stimulating hormone (r-HFSH) were compared in 103 WHO Group II infertile women with clomiphene citrate-resistant anovulation. Mono- or bifollicular development was induced in 88.1% of patients in group A compared with 76.1% in group B. Ovulation and pregnancy rates were higher in group A (71.4% and 33.3%, respectively) than in group B (63.0% and 20%), but these differences were not statistically significant. Additionally, the total number of follicles that were >10 mm diameter was lower in group A than group B (3.0 ± 2.6 versus 6.3 ± 6.5; P < 0.0001), as was the oestradiol concentration (504 ± 477 pg/​ml versus 988 ± 740 pg/​ml; P < 0.03). The median dose of FSH (75 IU ampoules) used per cycle was 11 ampoules in group A and 12.5 in group B. In terms of the incidence of ovarian hyperstimulation syndrome, no differences were recorded between the two groups. The results demonstrated that r-HFSH is effective and safe in both these treatment protocols. The chronic low dose regimen was associated with a trend towards a higher rate of mono- or bifollicular development, without jeopardizing the incidence of pregnancy.
Terms of Use
  • Copyright (C) 1998, European Society of Human Reproduction and Embryology
Language
  • English
Contributed by
OAIster

Get this edition

  • Set up My libraries

    How do I set up "My libraries"?

    In order to set up a list of libraries that you have access to, you must first login or sign up. Then set up a personal list of libraries from your profile page by clicking on your user name at the top right of any screen.

  • All (1)
  • Unknown (1)
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.

User activity


e.g. test cricket, Perth (WA), "Parkes, Henry"

Separate different tags with a comma. To include a comma in your tag, surround the tag with double quotes.

Be the first to add a tag for this edition

Be the first to add this to a list

Comments and reviews

What are comments? Add a comment

No user comments or reviews for this version

Add a comment