1990, English, Article edition: Psychotogenic Drug Use and Neuroleptic Response Bowers, Malcolm B.; Mazure, Carolyn M.; Nelson, J. Craig; ...

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Physical Description
  • text/​html
Published
  • Oxford University Press
  • 1990-01-01 00:00:00.0
Language
  • English

Edition details

Title
  • Psychotogenic Drug Use and Neuroleptic Response
Author
  • Bowers, Malcolm B.
  • Mazure, Carolyn M.
  • Nelson, J. Craig
  • Jatlow, Peter I.
Published
  • Oxford University Press
  • 1990-01-01 00:00:00.0
Physical Description
  • text/​html
Subjects
Notes
  • When fixed doses of haloperidol or perphenazine were used in two separate studies, we found that psychotic males with a prior history of psychotogenic drug use had a poorer early neuroleptic response even in the early stages of their psychotic disorder than psychotic males who had not previously used significant amounts of psychotogenic drugs. Relative neuroleptic refractoriness may be characteristic of some dual diagnosis patients at the beginning of their illness. Antecedent psychotogenic drug use may contribute to the development of psychosis and to relative neuroleptic refractoriness by means of effects upon dopaminergic mechanisms.
Terms of Use
  • Copyright (C) 1990, Maryland Psychiatric Research Center
Language
  • English
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