2009, English, Article edition: Protein short loop prediction in terms of a structural alphabet. Tyagi, Manoj; Bornot, Aurélie; Offmann, Bernard; ...

User activity

Share to:
 
Bookmark: http://trove.nla.gov.au/version/201001
Physical Description
  • text
Published
  • HAL - CCSD
  • 2009
Language
  • English

Edition details

Title
  • Protein short loop prediction in terms of a structural alphabet.
Author
  • Tyagi, Manoj
  • Bornot, Aurélie
  • Offmann, Bernard
  • De Brevern, Alexandre
Published
  • HAL - CCSD
  • 2009
Physical Description
  • text
Subjects
Notes
  • Loops connect regular secondary structures. In many instances, they are known to play crucial biological roles. To bypass the limitation of secondary structure description, we previously defined a structural alphabet composed of 16 structural prototypes, called Protein Blocks (PBs). It leads to an accurate description of every region of 3D protein backbones and has been used in local structure prediction. In the present study, we used our structural alphabet to predict the loops connecting two repetitive structures. Thus, we showed interest to take into account the flanking regions, leading to prediction rate improvement up to 19.8%, but we also underline the sensitivity of such an approach. This research can be used to propose different structures for the loops and to probe and sample their flexibility. It is a useful tool for ab initio loop prediction and leads to insights into flexible docking approach.
  • HAL:inserm-00396485, version 1
  • HAL:http:/​/​www.hal.inserm.fr/​inserm-00396485/​en/​
  • PUBMED:19625218
  • DOI:10.1016/​j.compbiolchem.2009.06.002
Language
  • English
Contributed by
OAIster

Get this edition

  • Set up My libraries

    How do I set up "My libraries"?

    In order to set up a list of libraries that you have access to, you must first login or sign up. Then set up a personal list of libraries from your profile page by clicking on your user name at the top right of any screen.

  • All (2)
  • Unknown (2)
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.

User activity


e.g. test cricket, Perth (WA), "Parkes, Henry"

Separate different tags with a comma. To include a comma in your tag, surround the tag with double quotes.

Be the first to add a tag for this edition

Be the first to add this to a list

Comments and reviews

What are comments? Add a comment

No user comments or reviews for this version

Add a comment