English, Article edition: Health Utilities Using the EQ-5D in Studies of Cancer A. Simon Pickard; Caitlyn T. Wilke; Hsiang-Wen Lin; ...

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Physical Description
  • article
Language
  • English

Edition details

Title
  • Health Utilities Using the EQ-5D in Studies of Cancer
Author
  • A. Simon Pickard
  • Caitlyn T. Wilke
  • Hsiang-Wen Lin
  • Andrew Lloyd
Physical Description
  • article
Notes
  • Cancer is one of the most frequent disease-specific applications of the EQ-5D. The objective of this review was to summarise evidence to support the validity and reliability of the EQ-5D in cancer, and to provide a catalogue of utility scores based on the use of the EQ-5D in clinical trials and in studies of patients with cancer. A structured literature search was conducted in EMBASE and MEDLINE to identify papers using key words related to cancer and the EQ-5D. Original research studies of patients with cancer that reported EQ-5D psychometric properties, responses and/​or summary scores were included. Of 57 identified articles, 34 were selected for inclusion, where 12 studies reported evidence of validity or reliability and 31 reported EQ-5D responses or summary scores. The majority of investigations using the EQ-5D concerned patients with prostate cancer (n_=​_4), breast cancer (n_=​_4), cancers of the digestive system (n_=​_7) and Hodgkin and/​or non-Hodgkin lymphoma (n_=​_3). Mean index-based scores ranged from 0.33 (SD 0.4) to 0.93 (SD 0.12) and visual analogue scale scores ranged from 43 (SD 13.3) to 84 (SD 12.0) across subtypes of cancer. A substantial and growing body of literature using the EQ-5D in cancer that supports the validity and reliability of EQ-5D in cancer has emerged. This review provides utility estimates for cancer patients across a wide range of cancer subtypes, treatment regimens and tumour stage(s) that may inform the modelling of outcomes in economic evaluations of cancer treatment.
  • Cancer, Quality-of-life, Utility-measurement
  • RePEc:wkh:phecon:v:25:y:2007:i:5:p:365-384
Language
  • English
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