English, Article edition: Clinical and Economic Considerations of Empirical Antibacterial Therapy of Febrile Neutropenia in Cancer George Dranitsaris

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Bookmark: http://trove.nla.gov.au/version/119771
Physical Description
  • article
Language
  • English

Edition details

Title
  • Clinical and Economic Considerations of Empirical Antibacterial Therapy of Febrile Neutropenia in Cancer
Author
  • George Dranitsaris
Physical Description
  • article
Notes
  • Febrile neutropenia is a condition that can develop in patients with cancer following the administration of myelosuppressive chemotherapy or radiation therapy. The current standard of patient management involves the empirical use of a combination of antibacterials or a single broad spectrum agent to offer extensive antibacterial coverage of both Gram-positive and Gram-negative microorganisms. Over the past 25 years, febrile neutropenia has changed from a condition that was fatal in over 50% of patients to a condition with an infection-related mortality rate of less than 10%. A major reason behind these extraordinary advances in patient care has been the many well-designed randomised trials of empirical antibacterial therapy that have been conducted over this period of time. In contrast to this finding, a review of the literature revealed limited economic data on the empirical treatment of febrile neutropenia in patients with cancer. Therefore, there is a definite need to conduct more pharmacoeconomic research in this area and to develop methods of implementing the findings of such studies.
  • Reviews-on-treatment, Immunocompromised-infections, Antibacterials, Immunocompromised-infections, Quality-of-life, Cost-analysis, Neutropenia, Cancer, Colony-stimulating-factors
  • RePEc:wkh:phecon:v:16:y:1999:i:4:p:343-353
Language
  • English
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