English, Article edition: Medico-Economic Analysis of Diacerein With or Without Standard Therapy in the Treatment of Osteoarthritis Francis Fagnani; Gilles Bouvenot; Jean-Pierre Valat; ...

User activity

Share to:
 
Bookmark: http://trove.nla.gov.au/version/119410
Physical Description
  • article
Language
  • English

Edition details

Title
  • Medico-Economic Analysis of Diacerein With or Without Standard Therapy in the Treatment of Osteoarthritis
Author
  • Francis Fagnani
  • Gilles Bouvenot
  • Jean-Pierre Valat
  • Thomas Bardin
  • Laurent Berdah
  • Antoine Lafuma
  • Isabelle Bono
  • Evelyne Eschwege
  • Renee- Liliane Dreiser
Physical Description
  • article
Notes
  • This 9-month pragmatic study compared 2 therapeutic regimens in the management of osteoarthritis of the hip and knee. Patients received either diacerein 100 mg/​day plus standard osteoarthritic therapy for 6 months, followed by a 3-month monitoring period without diacerein, or standard therapy alone for the entire 9-month period. A total of 207 patients with osteoarthritis of the knee and hip were enrolled. Improvements in Lequesne's functional index and quality-of-life scores (revised Arthritis Impact Measurement Scales Health Status Questionnaire and Nottingham Health Profile), and decreases in nonsteroidal anti-inflammatory drug and analgesic consumption were significantly greater with diacerein plus standard therapy than with standard therapy alone. The overall assessment of therapy by patients was good or excellent for 60% of those who received diacerein plus standard therapy, compared with 26% who received standard therapy alone. Medical and paramedical procedures carried out in addition to those stipulated in the protocol (medical consultations, physiotherapy, nursing, etc.), osteoarthritisrelated, were fewer and less costly in the diacerein plus standard therapy group than in the standard therapy group. The average outpatient cost (in 1995 French francs) of osteoarthritis treatment in the standard therapy group was FF2272 compared with FF2360 in the diacerein plus standard therapy group. The cost-effectiveness ratios per point scored on Lequesne's index were FF1893 for the standard therapy group and FF1072 for the diacerein plus standard therapy group, leading to a saving of 43% with diacerein plus standard therapy. The marginal cost (additional cost corresponding to the clinical benefit obtained by adding diacerein to standard treatment) was FF88 per point scored on Lequesne's index.
  • Diacerein, Osteoarthritis, Quality-of-life, Pharmacoeconomics, Cost-analysis, Antirheumatics, Nonsteroidal-antiinflammatories, Physiotherapy, Analgesics
  • RePEc:wkh:phecon:v:13:y:1998:i:1-part-2:p:135-146
Language
  • English
Contributed by
OAIster

Get this edition

  • Set up My libraries

    How do I set up "My libraries"?

    In order to set up a list of libraries that you have access to, you must first login or sign up. Then set up a personal list of libraries from your profile page by clicking on your user name at the top right of any screen.

  • All (1)
  • Unknown (1)
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.
None of your libraries hold this item.

User activity


e.g. test cricket, Perth (WA), "Parkes, Henry"

Separate different tags with a comma. To include a comma in your tag, surround the tag with double quotes.

Be the first to add a tag for this edition

Be the first to add this to a list

Comments and reviews

What are comments? Add a comment

No user comments or reviews for this version

Add a comment