Normie Rowe's professional singing career began in 1964 when he was spotted performing by radio personality Stan Rofe. Rofe arranged for him to appear at Melbourne dances and discos backed by instrumental groups like The Thunderdbirds, The Impostors and finally The Playboys, who became his permanent band until 1967. By 1965 he was making regular appearances on local television programs, including Teen Scene and The Go!! Show. Signing with Brisbane-based independent label Sunshine, Rowe released his first single Gershwin's It Ain't Necessarily So in April 1965. Rowe recorded a number of successful ballads and pop songs throughout 1965, including Que Sera Sera (1965), I Who Have Nothing (1965), Tell Him I'm Not Home (1965), and Shakin' All Over (1965), fostering his image as the epitome of the clean-cut pop idol of the mid-1960s. In mid-1965 he joined the Easybeats, Bobby & Laurie and M.P.D. Ltd on 'The Big Four' national tour playing to huge crowds around the country.
In August 1966 Rowe travelled to the UK to further his career. He recorded four new singles with producers Trevor Kennedy and John Carter and toured extensively with performers such as Julie Driscoll, The Spencer Davis Group, Brian Auger and The Trinity, Gene Pitney and The Troggs. In March 1967 he toured the UK with The Playboys. Together they also toured North America in support of Roy Orbison and represented Australia at Expo '67 in Montreal.
In September 1967 Rowe received a call-up for compulsory military service. The following two years included active service in Vietnam with the A Squadron, 3rd Cavalry Regiment, which dramatically curtailed his music career. Returning to the music industry in 1970 he released the minor hit Hello. In the 1970s Rowe concentrated on the club and hotel circuit, as well as performing on variety television shows such as The Don Lane Show and The Mike Walsh Show. During the 1980s and 1990s he moved into acting and musical theatre, including an extended role in the TV soap opera Sons & Daughters, and the role of Jean Valjean in Cameron Macintosh's Sydney production of Les Miserables in 1987.
In 2000 Rowe released a new album, Missing In Action, and in 2002 he toured Australia with the Long Way To The Top tour which featured prominent Australian rock acts from the 1950s to the present, including Little Pattie, Masters Apprentices and Stevie Wright.
Rowe closely identifies himself with Vietnam veterans groups and actively supports them, including helping to organise Vietnam Veteran's Welcome Home and Vietnam Veteran's National Memorial. Rowe has also been closely involved the Variety Clubs of Australia.